In these two studies, people took between In two clinical studies that each lasted 6 months, HAM-A scores decreased improved by 2. Social anxiety disorder is a type of anxiety felt during interactions with other people.
Symptoms can include fear of being judged by others, sweating, shakiness, fast heart rate, and avoiding social situations. Effexor XR has been found to be effective for treating social anxiety disorder. There is maximum score of points, with higher scores meaning worse social anxiety disorder.
A decrease in LSAS scores is related to an improvement in symptoms of social anxiety disorder. In clinical studies , people with social anxiety disorder took either Effexor XR or a placebo. The studies lasted for 3 and 6 months. Doses of Effexor XR ranged from 75 mg to mg once a day. At the end of the studies, LSAS scores decreased improved by This means Effexor XR controlled their symptoms more effectively than a placebo.
Panic disorder is a type of anxiety in which you have repeated and unexpected panic attacks feelings of very bad anxiety. Panic attacks can last anywhere from 5 to 30 minutes. Effexor XR has been found to be effective in treating panic disorder with or without agoraphobia.
In clinical studies , people with panic disorder took either Effexor XR or a placebo for 3 months. The dosage range of Effexor XR was 75 mg to mg once a day. These studies found that people who took Effexor XR were about 2. A full-symptom panic attack is one that involves all of the usual symptoms, including rapid heart rate, shakiness, nausea, and fear of losing control.
A boxed warning is the strongest warning required by the FDA. It is used to alert healthcare professionals and patients about the risk of serious side effects seen with the drug. The Effexor XR boxed warning describes an increased risk of suicidal thoughts and behaviors in young people who take Effexor XR.
The increased risk is seen in children under 18 years old and in adults ages 24 years old and younger. All antidepressants carry this warning, not just Effexor XR. In addition to the uses listed above, Effexor XR may be used off-label.
However, Effexor XR may be used off-label for this condition. However, it may be used off-label for this purpose. The American Academy of Family Physicians recommends venlafaxine the active drug in Effexor XR as a second-choice option for preventing migraine headaches. Treatment guidelines from the American Academy of Neurology state that venlafaxine is probably effective for preventing migraine headaches and should be considered as a treatment option. Treatment guidelines from the Endocrine Society recommend the use of antidepressants such as venlafaxine the active drug in Effexor XR to treat vasomotor symptoms hot flashes, night sweats, and flushing.
Effexor XR is available as a brand-name and generic medication. The generic form is a venlafaxine extended-release capsule. Effexor XR can cause mild or serious side effects. The following lists contain some of the key side effects that may occur while taking Effexor XR. These lists do not include all possible side effects. For more information on the possible side effects of Effexor XR, talk with your doctor or pharmacist.
They can give you tips on how to deal with any side effects that may be bothersome. Most of these side effects may go away within a few days or a couple of weeks. Call your doctor right away if you have serious side effects. You may wonder how often certain side effects occur with this drug. As with most drugs, some people can have an allergic reaction after taking Effexor XR.
Symptoms of a mild allergic reaction can include:. A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include:. Call your doctor right away if you have a severe allergic reaction to Effexor XR. Weight gain and weight loss have occurred in clinical studies of Effexor XR. Nausea is a common side effect of Effexor XR. If you have nausea while taking Effexor XR, talk with your doctor or pharmacist about ways to minimize this side effect.
Insomnia trouble sleeping is a common side effect of Effexor XR. If you have trouble sleeping while taking Effexor XR, talk with your doctor. They can recommend ways to reduce this side effect. There is an increased risk of suicidal thoughts and behavior in young people up to 24 years old who take antidepressants, including Effexor XR. This increased risk is seen in young people who have major depressive disorder or other psychiatric conditions. Effexor XR has a boxed warning for this side effect.
Young people starting Effexor XR should be monitored closely for worsening depression, unusual behavior, and suicidal thoughts and behavior. There are also other side effect concerns if children take this drug. In clinical studies lasting 8 to 16 weeks, many children who took Effexor XR had a lack of appetite. This may have contributed to weight loss seen in children within the study. Longer studies lasting up to 6 months showed that children taking Effexor XR did not gain as much weight as other children in the same age group.
This was especially true in children under the age of 12 years old. In clinical studies , children who took Effexor XR grew in height more slowly than typical children in their age group. This difference in growth was more dramatic for children under the age of 12 years old than for those ages 12 years and older. Typically, your doctor will start you on a low dosage. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect.
The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs. The maximum dosage for MDD is mg once daily.
However, daily dosages of mg or higher may be needed to treat MDD in some people. This would be considered an off-label nonapproved use. The usual starting dosage of Effexor XR for panic disorder is After 7 days, the dosage can be increased if needed. The maximum dosage for panic disorder is mg once daily. If you miss a dose of Effexor XR, take it as soon as you remember.
Never take two doses at once. This will raise your risk of serious side effects. A medication timer may be useful, too. Effexor XR is meant to be used as a long-term treatment. Patients, their families, and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia.
All patients being treated with antidepressants for any indication should watch for and notify their health care provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment. Last Updated: January This information is being provided as a community outreach effort of the College of Psychiatric and Neurologic Pharmacists. This information is for educational and informational purposes only and is not medical advice.
This information contains a summary of important points and is not an exhaustive review of information about the medication. Always seek the advice of a physician or other qualified medical professional with any questions you may have regarding medications or medical conditions.
Never delay seeking professional medical advice or disregard medical professional advice as a result of any information provided herein. The College of Psychiatric and Neurologic Pharmacists disclaims any and all liability alleged as a result of the information provided herein.
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Advocacy Policy Priorities. Advocacy Policy Platform. Advocacy Crisis Intervention. Advocacy State Fact Sheets. Venlafaxine belongs to a class of antidepressant drugs called serotonin norepinephrine reuptake inhibitors SNRIs. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
SNRIs work by increasing the levels of substances called serotonin and norepinephrine in your brain. Having more serotonin and norepinephrine in your brain can improve your symptoms of depression and anxiety.
Venlafaxine oral tablet may cause drowsiness. It may also affect your ability to make decisions, think clearly, or react quickly. You should not drive, use heavy machinery, or do things that require you to be alert until you know you can function normally. Venlafaxine may also cause other side effects. If these effects are mild, they may go away within a few days or a couple of weeks.
Call your doctor right away if you have serious side effects. Serious side effects and their symptoms can include the following:. Disclaimer: Our goal is to provide you with the most relevant and current information.
However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history. Venlafaxine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works.
This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully. Do not take these drugs with venlafaxine. When used with venlafaxine, these drugs can cause dangerous effects in your body. Examples of these drugs include:. Taking venlafaxine with certain medications raises your risk of side effects. When certain drugs are used with venlafaxine, they may not work as well.
This is because the amount of these drugs in your body may be decreased. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. If you have an allergic reaction, call your doctor or local poison control center right away.
If your symptoms are severe, call or go to the nearest emergency room. Taking it again could be fatal cause death. Do not drink alcohol with venlafaxine. Drinking alcohol raises your risk of sleepiness from venlafaxine.
This may affect your ability to make decisions, think clearly, and react quickly. If you drink alcohol, talk to your doctor. For people with liver disease: If you have a history of liver disease, your liver may not process this drug as quickly as it should.
This could lead to a buildup of this drug in your body. Your doctor may start you on a reduced dosage. If they increase your dosage later, they will monitor you closely. Swallow the mixture of applesauce and medicine right away without chewing. Drink a glass of water so all of the medicine is swallowed. The dose of this medicine will be different for different patients.
Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
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